[4] In April 2018, Thomas More University (then Thomas More College), which had been an NAIA member before moving to NCAA Division III in 1990, announced that it had been formally invited to rejoin the NAIA in the 2019–20 academic year as a member of the Mid-South Conference.

[6] In 2020, Bethel University became a Mid-South full member, brought track and field back to the MSC, and transferred all sports other than football and archery to the conference (prior to that, Bethel was an associate member of the MSC for football and archery only); additionally, Freed–Hardeman and UT Southern, then known as Martin Methodist College, also joined Mid-South.

[7] In December 2020, Life University also announced its departure from the MSC for the Southern States Athletic Conference for the 2022–23 academic year.

[8] Most recently, Thomas More announced in August 2021 that it would return to the NCAA, but this time in Division II as a member of the Great Midwest Athletic Conference (G-MAC).

[10] Then in July 2022, the Appalachian Athletic Conference announced it would add football as a sponsored sport.

[10] Later, the Appalachian Division folded when the AAC announced to sponsor the sport for the 2022 fall season, leaving the Mid-South with 9 football members.