Middelburg (Afrikaans pronunciation: [ˈmədəlbœrχ]) is a town in the Eastern Cape province of South Africa, in the Great Karoo.

The adjacent Grootfontein College of Agriculture was established as a military camp and training centre for British troops.

[3] In 1910 the Union of South Africa took control of the farm after which the Grootfontein School of Agriculture was established in 1911.

[6] Jozua François Naudé, Pastor in the Dutch Reformed Church, was born in Middelburg EC in 1873.

Other well known South Africans who were born or lived in Middelburg include Eddie Stuart (Footballer), Steven Sykes (Rugby player), Keanu Vers (Rugby Player), Arthur Lennox Ochse (Cricketer), John James Clements (recipient of the Victoria Cross), Eric Rosenthal (historian and author), Cecily Norden (Horse industry), John Phillip Harison Acocks (botanist), Colin Turpin, Reader in Law at Clare College, Cambridge .