Middle Grove is a hamlet in the town of Greenfield, New York.

Middle Grove has a post office with ZIP code 12850.

The first sawmill in the town of Greenfield was established here in 1786, and it was the site of several paper mills.

[5] The trailheads of the Hennig Preserve are located in Middle Grove.

The preserve is 606 acres (245 ha) of forests, creeks, and ponds open for hiking and cross-country skiing.