Naming of wards for several governors and medical staff of the hospital began with wards Percy, Clayton, Villeneau and Pyke, named after Hugh Percy, 1st Duke of Northumberland, Sir Kenrick Clayton, John Villeneau and the benefactor Pyke, respectively.

[1] The hospital had been completely rebuilt, on the same site and in stages, without ever being closed, paid for by more than £1 million of donations from members of the public.

The motto of the medical school, Miseris Succurrere Disco, was provided by one of the deans, Dr William Cayley, from Virgil's passage about Queen Dido aiding a shipwreck: Non ignara mali, miseris succurrere disco ("Not unacquainted with misfortune myself, I learn to succour the distressed").

[1] The main hospital building in Mortimer Street was sold to developer Project Abbey (Guernsey) Ltd, a company controlled by Christian and Nick Candy, and was demolished in 2008.

[9] The site was purchased by Clive Bush and Daniel Van Gelder's Exemplar Properties and Aviva Investors in July 2010.

[13] The new development, which combines 295 homes with 240,000 square feet (22,000 m2) of offices, including the regional headquarters for cosmetics multinational Estée Lauder, was completed in 2016.

The chapel was not formally opened until 1929, by which time much of the lavish interior decoration of marbles and mosaic in a mix of Italian gothic and romanesque styles had been added, giving it the appearance it broadly retains today.

[17] The chapel fabric and interior was subject to a £2m restoration, and the building re-endowed with maintenance funds by Exemplar Properties.

The Acts of Mercy were painted in 1912 by Frederick Cayley Robinson, a distinctive yet elusive British artist, after being commissioned by Sir Edmund Davis, one of the governors of the hospital.