In 1793, he renamed the county Middlesex and created the settlement of London, intending for the new capital of Upper Canada to be located there.
The regiment formed part of the 2nd Militia Brigade under Lt-Col. Christopher Hamilton, which served in Col. Hercules Scott's force.
The force advanced from Twelve Mile Creek and halted early on the morning of July 25 at Shipman's Corners.
[5] Around 1:00 p.m., the force received orders to rendezvous with Col. Brown at Lundy’s Lane, and they advanced to the battlefield, joining the engagement that afternoon.
[13] With the outbreak of the Rebellions of 1837-1838, the Middlesex Militia was placed on active duty in the county and was tasked with apprehending rebels from the area who were gathering under the command of Charles Duncombe.
The schooner Anne, supporting the rebel attack, sailed alongside the mainland firing on positions at Fort Malden.
The 2nd Middlesex Light Infantry, under Col. Thomas Radcliff, and other local regiments returned fire, disabling the helmsman and damaging the rigging.
Both regiments would serve on active duty during the Fenian Raids and many veterans would receive the Canada General Service Medal.