Middleton, often known as Middleton-by-Youlgreave or Middleton-by-Youlgrave to distinguish it from nearby Middleton-by-Wirksworth, is a village in the Peak District, Derbyshire, England.

This manor was mentioned in the Domesday book as belonging to Henry de Ferrers;[2] it included a mill and was worth sixteen shillings.

Middleton Castle, a fortified manor house, was built in the early seventeenth century, and saw some fighting during the English Civil War.

Christopher Fulwood attempted to raise a Royalist force from his base in the Castle, but on 16 November 1643, Roundhead troops raided the house and killed him.

Thomas Bateman rebuilt most of the village in the 1820s, incorporating the mullioned windows of earlier buildings to retain something of its traditional appearance.