Midlothian Independent School District is a public school district based in Midlothian, Texas, United States.

In addition to the majority of Midlothian, the district serves parts of Cedar Hill, Grand Prairie, Mansfield, Ovilla, Venus, and Waxahachie, as well as rural areas in northwestern Ellis County.

[3] In 2015, the district received the "Met Standard" rating by the Texas Education Agency.

All 9 individual Midlothian ISD campuses also met the standard in 2015.

This includes its partnership arrangement with Texas A&M-Commerce and most recently Tarleton State University.