The original four members were the Chicago Zephyrs, Rockford Foresters, Southland Vikings and Will County CrackerJacks.

Two of the teams (Illinois and Will County) failed to complete the season schedule.

Six teams made up the 2013 season as the league welcomed the Lexington Snipes, replacing DeKalb County.

MCL stayed steady with six teams with the addition of the Joliet Admirals (2014) and Michigan City Lakers (2015) replacing two teams (Rockford in 2014; Chicago in 2015) who ceased operations.

[5][6] The Crestwood Panthers, the newest team in the Midwest Collegiate League, replaced the Michigan City Lakers before the 2017 season.