Located 45 kilometres east of Tel Aviv on road 505 and adjacent to the Palestinian village of Qusra, it is organised as a community settlement and falls under the jurisdiction of Shomron Regional Council.

One of the reasons for choosing this location was to provide a continuity of settlements along the Trans-Samaria Highway between Kfar Tapuah on the "mountain spine" and Ma'ale Efrayim in the Jordan Valley.

[citation needed] On March 1, 2006, Eldad Abir, a resident of Migdalim, married with two children, was shot at point blank range and killed by Palestinians while working in the local gas station.

[5] An influx of new residents between 2012 and 2017 dramatically changed the demographics of Migdalim which shifted from being a dominantly secular Israeli community to becoming mix of religious and nonreligious, with majority leaning to the first.

A Facebook group called “Saving Migdalim” was formed by residents who claim that their town was taken over and its non religious atmosphere has changed as result.