Capriles launched Últimas Noticias in 1941, after the pro-freedom measures implemented by Venezuelan President Medina Angarita.
In 1956 Capriles Ayala acquired the newspaper La Esfera.
On 3 February 1958, shortly after the end of the dictatorship of Marcos Pérez Jiménez on 23 January 1958, Capriles launched El Mundo, which for most of its existence was the only Venezuelan evening newspaper.
Capriles was elected to the Venezuelan Senate in 1968 on COPEI's party list and seven Capriles nominees were elected to the Venezuelan Chamber of Deputies, including the editor of El Mundo, Pedro Ramon Romero.
[3] Miguel is the father of Tanya Capriles Brillembourg, who is a renowned art collector, owner of the gallery exhibition space called Ideobox in Miami, and Board of Trustees member for the Museum of Fine Arts, Houston, the New World Symphony in Miami Beach, and the Museo Reina Sofia in Madrid and the grandfather of David Brillembourg who is the Director of the Babson College Latin American Institute and is an advisor to the SaludArte Foundation and a prominent entrepreneur with over 20 years’ of experience working with developing companies that take advantage of market opportunities in emerging technology.