Miguel Hernández Agosto (April 5, 1927 – March 18, 2016) was a Puerto Rican politician whose service in government spanned several generations.

Affiliated with the Popular Democratic Party (PPD), he started his political career as a Cabinet member, but eventually became a Senator at-large.

Hernández Agosto finished his bachelor studies in agricultural sciences from the University of Puerto Rico at Mayagüez at the age of 19.

Luis Muñoz Marín, who subsequently appointed him as Secretary of the Puerto Rico Department of Agriculture, a position he also held under the governorship of Roberto Sánchez Vilella.

After winning a bruising reorganization primary campaign in 1988 against former Governor Carlos Romero Barceló, he became State Chair of the Democratic Party of Puerto Rico, a post he held until 1992.