Miguel Arturo Layún Prado (born 25 June 1988) is a Mexican former professional footballer who played as a right-back.

Veracruz, he signed in 2009 for Italian club Atalanta, becoming the first Mexican player to play in the Serie A,[5] where he only made two substitute appearances.

In 2006, Miguel Layún began his professional career with Gallos Caliente Tijuana,[4] which was Queretaro reserve team in Primera "A".

Veracruz in his home state, Layún debuted in the Primera División during the Clausura 2007 tournament on 28 April against Necaxa.

[12] He made a second league appearance with the team against Cagliari on 1 November, again coming on as a substitute, replacing Nicola Madonna in the 66th minute of the match, which ended in a 3–0 defeat.

[17] On 14 December 2014, Layún captained América to the league title following a 3–1 aggregate victory over Tigres UANL in the finals.

[23] On 31 August 2015, it was announced that Layún would join Porto on a year-long loan deal with an option to buy for €6 million.

[26] On 28 May 2016, it was announced that Porto had signed Layún on a permanent deal, with the reported €6 million fee to be paid in two installments.

[27] On 30 January 2018, Layún joined Spanish La Liga outfit Sevilla on a loan deal that ran for the remainder of the 2017–18 season and included a buyout option.

[29] On 31 August 2018, he would make his debut with the team coming in as a substitute for Santi Cazorla at the 75th minute against Girona, where Villarreal lost 1–0.

[31] Despite interest from European clubs like Celta de Vigo and Milan for his services during the 2018 winter transfer season, Layun decided that financially and personally it was a better decision to be back in Mexico and still play at a high level.

On 3 June 2021, Layún returned to Club América signing a one-year deal, with the option of an additional year.

In 2013, Layún received his first national team call up by coach José Manuel de la Torre after his performances with Club América during the Clausura tournament.

He was selected for the 2013 CONCACAF Gold Cup held in the United States, with the entire squad being made up of players from the Mexican league.

Layún was called up again by interim coach Víctor Manuel Vucetich to participate in Mexico's last two World Cup qualifying matches against Panama and Costa Rica.