Don Miguel de Pedrorena (c. 1808–March 21, 1850) was a Spanish-born Californio ranchero, merchant, and a signer of the California Constitution in 1849.

Most of the Castilian race of the upper class are proud and aristocratic; but Don Miguel, though of high birth, was exceedingly affable, polite, gracious in manner and bearing, and, in every respect, a true gentleman.

He married a daughter of Prefect Estudillo and resided in San Diego until the time of his death on March 21, 1850, leaving three children.

During the last two or three years of his life those relatives became aware of his unfortunate circumstances and wrote to him repeatedly, urging him to come home to Spain and bring his family with him.

Popular with everybody in the department, the recollections of him by those who knew him were exceedingly pleasant.During the Mexican–American War Pedrorena supported the U.S. side, fighting at Fort Stockton.

This venture soon failed due to several factors including the absence of fresh water, its location in marshlands, and lack of support.

After his death, his widow and family built houses and corrals at Rancho El Cajon for their stock, and harvested large crops from the land, but his wife died shortly thereafter, February 3, 1851.