Michael Christopher Mayers (born December 6, 1991) is an American professional baseball pitcher who is a free agent.

In his junior year, he posted a 2.83 earned run average (ERA) over 92+1⁄3 innings pitched with 73 strikeouts and 37 walks.

He decided to forgo one remaining year of eligibility and avail himself to the Major League Baseball draft.

[6] He signed and made his professional debut with the GCL Cardinals before being promoted to the Peoria Chiefs, where he finished the season.

In 2015, Mayers was 2–4 with an ERA of 5.87 for the GCL Cardinals and Springfield, and underwent surgery for thoracic outlet syndrome (TOS).

In his debut, each of the first four batters he faced in the first inning reached base, and all scored on a grand slam by the fourth, first baseman Adrián González.

[11] In all, 10 of 14 batters reached base as Mayers surrendered nine earned runs, eight hits, and two walks, while recording four outs for an in-game ERA of 60.75.

Per the Elias Sports Bureau, he became the first major leaguer to surrender at least nine runs while advancing through fewer than two innings in his debut.

[14] During spring training 2018, Mayers pitched 12 scoreless innings, striking out 13, earning him a spot on the Opening Day roster.

[16] He was placed on the disabled list for the first time in his major league career on August 26 with right shoulder inflammation,[17] and activated on September 11.

[27] Working as both a starter and reliever in 2022, he made 24 total appearances and registered a 5.68 ERA with 45 strikeouts in 50.2 innings pitched.

[29] He was assigned to the Triple-A Omaha Storm Chasers to begin the 2023 season, where he made 8 starts and posted a 6.88 ERA with 29 strikeouts in 34.0 innings pitched.