He is known for directing Sky High (2005), Shrek Forever After (2010), Alvin and the Chipmunks: Chipwrecked (2011), Trolls (2016), The Lego Movie 2: The Second Part (2019), and Kung Fu Panda 4 (2024).

[citation needed] He graduated from Putnam City North High School, then subsequently moved to Los Angeles to attend the California Institute of the Arts.

The same year, he made his feature film directorial debut with the comedy Deuce Bigalow: Male Gigolo, starring Rob Schneider.

[1] He also worked as a voice actor for Advisor Wedgie (known as "Nerd" for most of the film) in Monsters vs. Aliens, and Andy "Jack" Beanstalk in Puss in Boots.

[5] On April 26, 2023, it was announced that Mitchell is set to direct the fourth installment in the Kung Fu Panda franchise, which was released on March 8, 2024.