After a year and a half in San Diego, Pagliarulo moved back to the American League when he joined the Minnesota Twins just before the start of the 1991 season.

At the time, the Orioles needed depth at third base with Leo Gómez on the disabled list but had been unsuccessful in its pursuit of the Cincinnati Reds' Chris Sabo.

In the Japan Series, Pagliarulo's Seibu team faced the Yomiuri Giants, featuring his 1991 Twins teammate Dan Gladden in a side story where either player could win another championship.

[citation needed] His son, Michael, was a member of the 2009 Ivy League champion Dartmouth Big Green baseball team.

[7] His daughter, Erica, was the leading scorer for the Rollins College Women’s Lacrosse team’s most successful season in program history.