Primarily an outfielder, White appeared in Major League Baseball for all or parts of three seasons (1963–65) for the Houston Colt .45s / Astros.

Mike White threw and batted right-handed, stood 5 feet 8 inches (1.73 m) tall and weighed 160 pounds (73 kg).

After one year in the Angels' farm system, he was drafted by another expansion team, the Colt .45s, during the winter before their debut 1962 season.

White batted .294 and .324 in successive seasons in the high minors before making his debut with the Colt .45s in September 1963.

White spent the entire 1964 campaign with Houston, primarily as a center fielder, and batted .271 with 76 hits in 89 games.