Commenced in February 1989, and opened on May 15, 1991, for the 100th anniversary of the writer's birth, the museum is located at No.13 on the Andriivskyi Descent and contains an exposition of nearly 2500 pieces that include Bulgakov's belongings, books, postcards, and photos — conveying the life and creativity of the writer and his surroundings.

The White Guard novel makes vivid references to the Andriyivskyy Descent, and the current plaque of the address at No.13 displays the street name the writer used in his book (No.13 Andreevsky spusk).

Inna Konchakovskaia (1902–85), daughter of the owner (who was a hero of that Bulgakov novel) and niece of composer Witold Maliszewski, preserved this unique house in Kyiv in the hard Soviet times.

[1] The museum staff conducts considerable studies and research, publishes unreleased material, and holds book-club meetings.

Oleksandr Tkachenko, the then culture minister, as well as Liudmyla Gubianuri, the museum director, opposed the calls.