[2] Hockey Hall of Famer Patrick Roy, the owner, general manager and head coach of the Remparts, liked Grigorenko so much he traded up in the Import Draft to select him.

[3] Earning selection to the All-Rookie and First All-Star Teams on 20 March 2012, Grigorenko was also nominated and chosen as the top professional prospect to play in the QMJHL during 2011–12 with the Mike Bossy Trophy.

[6] When the lockout ended in January, Grigorenko was invited to the Sabres' training camp, where he made the roster for the start of the season.

After being a healthy scratch for three games, Grigorenko made his Avalanche debut centering the fourth line, collecting an assist on a Jack Skille goal in a 3–0 victory over the Anaheim Ducks on 16 October 2015.

Grigorenko later secured a role on a scoring line through the midpoint of the year to play his first full season in the NHL, recording a career-high six goals and 27 points in 74 games.

While lacking the physicality for a lower-depth role, Grigorenko (mainly playing on the wing) collected ten goals for 23 points in 75 games for the cellar-dwelling Avalanche.

In the playoffs, Grigorenko continued to lead CSKA's offense, helping return the club to the Gagarin Cup finals, selected as the finals best forward in helping CSKA claim their first Championship in the KHL by scoring 6 points in the four-game series sweep against Avangard Omsk.

[23] On 20 April 2020, Grigorenko planned a return to the NHL, signing a one-year, $1.2 million contract with the Columbus Blue Jackets.

[25] After attending the Blue Jackets training camp, Grigorenko made the opening night roster, making his debut and playing his first NHL game in nearly four years in a 3-1 defeat to the Nashville Predators on 14 January 2021.

[26] Deployed in scoring line role, Grigorenko struggled to translate his offensive game and was reduced to a healthy scratch mid-way through the season.

He later returned to the lineup to finish with four goals and 12 points through 32 regular season games as the Blue Jackets missed the playoffs.

Grigorenko opted to return to Russia as an impending free agent, signing a three-year contract with his former club, CSKA Moscow of the KHL, on 3 July 2021.

[3] In 2011, after being selected by the Remparts in the CHL Import Draft, Grigorenko moved to Quebec City with his mother and Yuri.