Mikulášovice (German: Nixdorf) is a town in Děčín District in the Ústí nad Labem Region of the Czech Republic.

Mikulášovice consists of four municipal parts (in brackets population according to the 2021 census):[2] Mikulášovice is located about 23 kilometres (14 mi) northeast of Děčín and 40 km (25 mi) northeast of Ústí nad Labem.

It lies in the salient region of Šluknov Hook, on the border with Germany, adjacent to the municipal territory of Sebnitz.

[4] The company Mikov, producing the popular knife Rybička, has its seat in Mikulášovice.

The station Mikulášovice dolní nádraží on the railway line Děčín–Rumburk is located just behind the municipal border.