Mikulčice consists of two municipal parts (in brackets population according to the 2021 census):[2] Mikulčice is located about 6 kilometres (4 mi) southwest of Hodonín and 52 km (32 mi) southeast of Brno, on the border with Slovakia.

From the 6th until the 10th century, a Slavic fortified settlement existed 3 km southeast from the modern village on the site called Mikulčice-Valy.

The settlement was one of the main centres of the Great Moravian Empire, plausibly its capital city.

Excavations unearthed the remnants of twelve churches, a palace, and more than 2,500 graves (including a horse burial).

It includes an exhibition with archeological finds from this area, administered by the Masaryk Museum in Hodonín.