The Mileševa printing house (Serbian: Милешевска штампарија) was a printing house established in 1544 in the Mileševa monastery near Prijepolje, Ottoman Empire (modern day Serbia).

Activities connected with printing in Mileševa began when in 1518 or at the beginning of 1519 when Teodor Ljubavić, who was a hieromonk of Mileševa, travelled to Venice to learn printing skills.

[1] In 1543 Todor Ljubojević, a monk in Mileševa and son of Božidar, was sent to Venice to join his brother Đurađ and to buy a printing press for the monastery.

He was accompanied by Mileševa monk Sava and by Mardarije who was a hegumen of the Banja Monastery near Priboj.

[8] Trebnik was printed by Deak Damjan and Milan from Obna (region around river Kolubara).