The Miles Brewton House is a National Historic Landmark residential complex located in Charleston, South Carolina.

It is one of the finest examples of a double house (a reference to the arrangement of four main rooms per floor, separated by a central stair hall) in Charleston, designed on principles articulated by Andrea Palladio.

Located on two acres, its extensive collection of dependencies makes it one of the most complete Georgian townhouse complexes in America.

[2][4] The Miles Brewton House is set on the west side of King Street near the southern tip of the Charleston peninsula.

The porch is supported by columns (Doric on the first floor, Ionic on the second), and is topped by a fully pedimented and dentillated gable.

[4] The entrance to the house includes one of the few remaining chevaux de frise, or defensive spikes that were used to keep out intruders, and commonplace amidst concerns of slave revolt.

Elected as a delegate to the Second Continental Congress, he was traveling to Philadelphia with his family in late August 1775 when their ship went down and they were all lost at sea.