Millheim is an unincorporated settlement in Cinque Hommes Township in Perry County, Missouri, United States.

The name Millheim is most probably an American corruption of the German Müllheim, meaning ‘mill home’.

[3] A well-known mill was built at the present-site of Millheim as early as 1856 by Rudolph Conrad and Mike Eddleman, and a post office was established in 1891.

[3] Millheim is situated in Cinque Hommes Township, and is located approximately eight miles south of Perryville.

This Perry County, Missouri state location article is a stub.