Millie Perkins (born May 12, 1936) is an American retired film, television actress and model known for her debut film role as Anne Frank in The Diary of Anne Frank (1959), and for her supporting actress roles in two 1966 Westerns, The Shooting and Ride in the Whirlwind, both directed by Monte Hellman.

Perkins had never studied nor sought to be an actress, but director George Stevens saw her photo and tried to convince her to read for the part.

Perkins received almost universally excellent reviews for her portrayal of Frank, although the film was less of a box-office success than expected.

She played the female lead in both of Jack Nicholson's inaugural productions The Shooting and Ride in the Whirlwind – shot side-by-side in 1965 – and in 1968 co-starred in Wild in the Streets which was written by her then-husband Robert Thom.

Recent to her retirement, she was honored in the 2004 action-adventure video game Grand Theft Auto: San Andreas, in which one of the storyline girlfriends to protagonist Carl "CJ" Johnson, voiced by Orfeh, was named after her.

In December 1964 (reportedly on Christmas day), Perkins married writer and director Robert Thom,[8] who wrote the script for the popular 1968 movie Wild in the Streets, in which she appeared.