Due to an error in the creation process, Milton is tender and good-natured instead of being sinister.

[3] He was created by mad scientist Professor Montgomery Weirdo and his assistant Count Kook, who lived in a haunted house on Horror Hill.

Milton was created not of individual body parts, but rather in a mold from such liquids as "essence of terror" and "sinister sauce."

Out of fear of his creation destroying him, Professor Weirdo intended to add just a touch of the aforementioned tincture of tenderness to the mold, but Count Kook bumped the Professor's elbow, resulting in too much of the tincture being added to the mix.

Other characters in the series included Fangenstein, a biker monster apparently inspired by Marlon Brando, his sidekick Abercrombie the Zombie (who is sometimes Milton's friend), and Professor Weirdo's aunt, the witchy Aunt Hagatha.