[4] Mineola came into existence when the railroads built lines through the eastern part of the state.

A city government was organized in 1873, a post office opened in 1875, and the town was incorporated in 1877, but a fire in the 1880s destroyed 18 buildings.

[5] During the community's first 60 years, farm products included cotton, livestock, fruit, and berries.

Highway improvement, the Magnolia Pipeline Company gas line, and the establishment of a railroad terminal caused growth during the 1920s, and the discovery of oil in parts of Wood County and construction of a T&P railroad shop spurred the economy during the 1940s.

Meredith Hall Civic Center, completed in 1977, is used by large and small groups for varied events.

The manufacture of women's clothing, sporting goods, electronic connectors, fertilizer, and cattle feed, and the packaging of dry beans and meat provide employment for many people.

The Wood County Airport, 5 nautical miles (9.3 km; 5.8 mi) north of Mineola, was completed in 1984.

In 2023, Max aired How to Create a Sex Scandal, a three-part documentary about charges of child sexual abuse that allegedly took place in Mineola in 2005.

[6] Mineola enjoys weather typical of East Texas, which is unpredictable, especially in the spring.

Mineola's humid subtropical climate is typical of the Southeast United States.

Situated between Front and Commerce Streets and alongside the Union Pacific Railroad tracks the park is a joint effort between the Mineola Landmark Commission, the Parks & Open Spaces Board and the City of Mineola.

KMOO-FM (99.9 MHz FM, "K-Moo") is a radio station broadcasting a country music format.

Licensed to Mineola, Texas, United States, the station serves the Tyler-Longview area.

[17] The railroad tracks which run through the southern portion of Wood County and through Mineola are currently owned and operated by Union Pacific.