[5] Ultimately, the ministers are responsible to the Parliament of New South Wales.

The role of a government advisor and administrator on medical policy in New South Wales began in 1914, with the appointment of Fred Flowers as the Minister for Public Health.

[7] This department was abolished in 1913 and was replaced by the "Office of the Director-General of Public Health" which, like its predecessor, operated under the supervision of the Colonial Secretary.

[8] The department existed until its abolition in 1972 with the passing of the Health Commission Act 1972 which created the "Health Commission of New South Wales" headed by the minister.

[10] The following individuals have served as Minister for regional health, or any precedent titles: