The Ministry of Defence of the Czech Republic (Czech: Ministerstvo obrany České republiky, MO ČR) is the primary agency of the Czech Republic responsible for the planning and carrying-out of defence policy.

It is the Czech Republic's ministry of defence.

It is the direct successor of the Czechoslovak Ministry of Defence.

The current Minister of Defence is Jana Černochová, in office since 17 December 2021.

This article about government in the Czech Republic is a stub.