The Ministry of Defence of Republic of Serbia (Serbian: Министарство одбране, romanized: Ministarstvo odbrane) is the ministry in the Government of Serbia which is in the charge of defending the Republic of Serbia from internal and external military threats.

The current minister is Bratislav Gašić, in office since 2 May 2024.

This is the organisation within the Ministry of Defence: This is a list of all the Ministers of Army (and the Acting Ministers of Army) of the Principality of Serbia and the Kingdom of Serbia from the creation of the post in 1862 to the creation of Yugoslavia after World War I, in the late 1918.

People's Radical Party Serbian Progressive Party Independent Radical Party Non-party This list includes Ministers of Defence from 1991 to 1993, and after the dissolution of the State Union of Serbia and Montenegro in 2006.

For previous ministers, see Ministry of Defense (Yugoslavia).