[1] The headquarters of the ministry are located at 2A Colville Street, on Nakasero Hill, in the Central Division of Kampala, the capital and largest city of Uganda.

The state minister for international affairs has been Henry Oryem Okello since 2005.

Since 1 March 2015, Philemon Mateke has been the state minister for regional affairs.

[7] It also has the following departments: During the 2019-2020 Hong Kong protests, Uganda was among the African countries that expressed support for China's approach.

[16]: 41  In October 2019, the Ministry of Foreign Affairs issued a statement that Uganda "firmly supports the one country, two systems policy of the People's Republic of China on the matter of Hong Kong and other areas" and that "Hong Kong's affairs are China's domestic affairs.