[1] The activities of the ministry are supervised directly by the President of Uzbekistan.

[1] The ministry is headed by the Minister of Foreign Affairs of Uzbekistan, currently Baxtiyor Saidov.

His First Deputy is Abdulaziz Kamilov who was the first foreign minister since the establishment of the ministry.

Other deputies are Rustam Tukhtabaev, Abdurahim Khodjaev, Anvar Solihbaev, Bahtiyar Islamov.

[2] The ministry is divided into several departments: represents tenure as Acting Minister