It is the central executive authority exercising state administration in the sphere of relations of the Republic of Tajikistan with foreign countries and international organizations.

The Ministry of Foreign Affairs of the Republic of Tajikistan has the status of a legal entity, its own seal, stamps, and bank accounts.

Over 65 years, the name of the foreign ministry of Tajikistan has changed 5 times:[2] On February 1, 1944, the Supreme Soviet of the USSR adopted a law granting the union republics powers in the field of foreign relations, which provided for the right of each union republic to enter into direct relations with foreign states.

By July, Ali Akhmedov was appointed People's Commissar for Foreign Affairs of the Tajik SSR, who worked in this post until 1946.

On July 20, 1992, President Rahmon Nabiyev issued a decree “On improving the structure of the bodies for managing foreign relations of the Republic of Tajikistan”, and on August 27, of that year, pursuant to the decree, the Cabinet of Ministers of adopted a resolution on the issues of the Ministry of Foreign Affairs, approving the structure of the central office of the ministry.