The Ministry of Health is a department of the Government of British Columbia which oversees the provincial healthcare system.

[5] The Department of Health and Welfare was formally established on October 1, 1946, with George Pearson as the inaugural minister.

On April 30, 2020, the Ministry published guidance alongside the BC Centre for Disease Control on interpreting the results of polymerase chain reaction (PCR) tests for detection of SARS-CoV-2, the virus that causes COVID-19.

[10] On October 19, 2022, Minister Adrian Dix introduced legislation to replace the Health Professions Act, the provincial law governing British Columbia's regulatory colleges, with the Health Professions and Occupations Act.

[12] In July 2023, Minister Dix appointed Allan Seckel to oversee the amalgamation process.