The Ministry of Industry, Science, Technology and Innovation (Khmer: ក្រសួងឧស្សាហកម្ម វិទ្យាសាស្ត្រ បច្ចេកវិទ្យា និងនវានុវត្តន៍, UNGEGN: Krâsuŏng Ŭssahâkâmm, Vĭtyéasastr, Bâchchékâvĭtyéa nĭng Nôvéanŭvôttân) is a government ministry responsible for industrial, science, technology, innovation policies in Cambodia.

Its name was changed from the Ministry of Industry and Handicrafts in March 2020, in response to the fourth Industrial Revolution.

[1][2] The current minister is HEM Vanndy.

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