The Ministry is headed by Cabinet Minister Mangal Lodha since 21 December 2024.

The Ministers Chamber and Head Office of the department is on 2nd Floor[1] of the iconic Mantralaya Building located on Madame Cama Road Mumbai.

{{Empty section|date=July 2024} Vivek janadhran shetye as chife head of PR management } Ministry has different departments and societies which look after skill development and entrepreneurship activities.

SDEED is responsible for execution of the Maharashtra State Innovative Startup Policy.

[2] Along with ministers, members from Civil Services of India lead department[3] Maharashtra State Skill Development Society (MSSDS) was established on 15 February 2011 under the Societies Registration Act 1860.