Founded in August 2004 as Minnesota RollerGirls by the Donnelly sisters, MNRD was one of the first 30 members of the Women's Flat Track Derby Association (WFTDA) by early 2006.

[4] Since 2005,[5] the league has played and practiced at the Roy Wilkins Auditorium[6] in Saint Paul, with capacity for up to 4,000 spectators for roller derby,[7] and average attendance ranging between 1,800 and 3,000 fans at MNRG events.

No skater or volunteer associated with the Minnesota Roller Derby is paid, nor do they profit based upon level of involvement or upon team wins.

Proceeds raised by the league pay for practice space rental, legal and promotional fees, as well as traveling costs to play other WFTDA members in other states and in other countries.

In August 2019, the league adopted its current name as Minnesota Roller Derby, "to better reflect the organization’s membership and community".

[23] MNRG hosted the 2009 North Central Regional Tournament, the "Brawl of America", at Roy Wilkins Auditorium, at which they came in ninth place.

[25] The tie (later upheld upon review by the WFTDA)[26] resulted from a scorekeeping correction made well after the end of play, avoiding a potential overtime jam[27] which ordinarily would have settled the score.

In 2013, the Women's Flat Track Derby Association realigned its competitive divisions to emphasize teams' win–loss record and difficulty of opponents rather than organizing by regions.

[65] Minnesota All-Stars Lynn "Juke Boxx" Klass and Melissa "Medusa" Arnold represented the United States on Team USA at the 2011 Roller Derby World Cup.

[66] In 2014, Juke Boxx returned to the Team USA roster, joined by Dana "Second Hand Smoke" Noss, for the 2014 Roller Derby World Cup.