Minnesota State Highway 4 (MN 4) is a 167.136-mile-long (268.979 km) highway in southwest and west-central Minnesota, which runs from Iowa Highway 4 at the Iowa state line (near Dunnell, MN and Estherville, IA), and continues north to its northern terminus at its interchange with Interstate Highway 94 near Sauk Centre and Melrose.

State Highway 4 serves as a north–south route between Sherburn, Saint James, Sleepy Eye, Fairfax, Hector, Paynesville, and Meire Grove in southwest and west-central Minnesota.

Fort Ridgely State Park is located on Highway 4 in Nicollet County on the Minnesota River.

The park is located south of Fairfax and northwest of New Ulm.

Grain elevators in Echols, Ormsby, Trimont, and Sherburn are aligned with the former M&StL route through each of these towns.