State Highway 48 serves as an east–west route between Hinckley, Cloverdale, and Danbury, WI.

Highway 48 crosses the Grindstone River on the eastern edge of Hinckley.

The route crosses the Kettle River in Barry Township near Hinckley.

Camp Nathanael is located 16 miles (26 km) east of Hinckley on Highway 48.

Lower speed limits are in place from Interstate 35 to just east of Grand Casino near Hinckley Road, and through Cloverdale, where a short 45 mph segment exists.