Klobučar was born in Zagreb on July 28, 1888, to a wealthy Jewish family of Herman and Marija (née Eisner) Ehrlich, and was raised with four siblings; Adolf, Ernest, Đuro and Hugo.

After the death of her father, her mother sent her away to gymnasium Sacré Cœur in Vienna.

After gymnasium, she was educated at the City and Guilds of London Art School.

Klobučar's body of work was small, because she painted only in particular moments of inspiration.

[1] Although she was forced to wear yellow star of David on her clothes, Klobučar survived the Holocaust.