As Dhaka expanded northward during the Pakistan period (1947–1971), Mirpur Road emerged as the city's main north–south axis, serving the new areas of Dhanmondi, Mirpur, and Uttara.

[1] Non-motorized transport was banned on Mirpur Road between Gabtoli and Russel Square in December 2002 as part of the Dhaka Urban Transport Project (DUTP) financed by the World Bank.

[2] Mirpur road is home to numerous buildings, skyscrapers, architectural structures etc.

Gonobhaban, the official residence of Prime Minister is also situated on Mirpur road.

Dhaka New Market, a traditional renowned market of Dhaka, where different sorts of commodities are found at a cheap rate, is situated on the southern part of Mirpur road near Nilkhet.