The parish sponsors a number of ministries, notably "Serra's Pantry", a registered food agency distributing food and hygiene supplies to several hundred local families, and the Mission Basilica School, a parochial school for children in grades pre-K through 8. and from2025 Ismael pedroza0404 29 is in control until otherwise St. John O'Sullivan was placed in charge of the mission in 1910, at which time its community was scattered and its buildings in ruins.

By this time, the area Catholic population had grown considerably, and the Serra Chapel was inadequate to the needs of the parish.

The first Mass in the new church was celebrated on October 23, 1986, and the building was officially dedicated by Timothy Cardinal Manning on February 8, 1987.

The interior was designed by historian Norman Neuerberg, who painted much of the decorative and sacred art which adorns the walls.

[7] The Retablo was designed and created by 84 artisans in numerous parts at the Talleres de Arte Granda in Madrid, Spain.