[10] During 2020, Mission acquired several more television stations, starting that March with Fox affiliates KMSS-TV in Shreveport, Louisiana, KPEJ-TV in Odessa, Texas, and KLJB in Davenport, Iowa, from Marshall Broadcasting Group for $49 million.

[12] They were followed up on July 13 by Nexstar transferring its option to purchase WPIX in New York City, a CW affiliate from The E. W. Scripps Company to Mission Broadcasting.

On August 7, Mission announced the purchases of CW affiliate KWBQ in Santa Fe, New Mexico, and its satellites and its MyNetworkTV sister KASY-TV in Albuquerque from Tamer Media LLC.

[17][18][19] Then on August 31, it was announced that Nexstar executed an option to purchase dual Fox and CW affiliate WNAC-TV in Providence, Rhode Island, for $64,000.

The option had been in place since 2003 when LIN TV owned sister station, then and now CBS affiliate WPRI-TV with Nexstar assigning the WNAC license to Mission.

[21] On May 17, 2023, Mission announced a deal to acquire MyNetworkTV affiliate WADL in Detroit (licensed to Mount Clemens) from founder Adell Broadcasting for $75 million.