The route starts at MS 1 near Lobdell, and it travels east through the Dahomey National Wildlife Refuge and Skene.

The highway was designated in 1955 along its current alignment, after the state had funded projects to improve the preexisting county road.

[5] East of Neblett Road, the route enters the Dahomey National Wildlife Refuge.

The first project was proposed in November, for grading and gravel surfacing a 2.82-mile (4.54 km) section of the road.

[9] A project to pave 10.452 miles (16.821 km) of the road in asphalt began one month later,[10] with a cost of $216,156 (equivalent to $2,458,540 in 2023).