Missouri H. Stokes (July 24, 1838 – November 27, 1910) was an American social reformer and writer of the long nineteenth century associated with the temperance movement.

While working in the missionary field and having charge of the Mission Day School in Atlanta, she found herself drawn into the crusade for temperance after it expanded into the South.

[2] Missouria (often written, "Missouri")[3] Horton Stokes was born in Gordon County, Georgia, July 24, 1838, in the home of her maternal grandfather, Stevens, which had been occupied by the missionaries to the Cherokee.

[2] Her paternal grandfather, Stokes, was a native of Ireland, who fought on the side of the Thirteen Colonies in the Revolutionary War, and at its close, settled in South Carolina.

John S. Wilson, principal of the Hannah More Female Seminary, from which institution she was graduated after a three-year course in the regular college studies.

John S. Wilson, D. D., pastor of the Presbyterian Church and principal of the Hannah More Female Institute, from which school she graduated in 1858, after a three year's course in the usual collegiate studies.

Stokes showed an early liking for teaching, and after graduating, in 1858, she taught for several years, including those of the Civil War.

Her widowed sister-in-law and young nephew were then added to the household, and she gladly devoted herself to home duties, abandoning all teaching for several years, excepting a music class and a few private pupils.

[2] Stokes was severely injured some time before her death, her leg being broken, and on account of her advanced aged, recovery had been very slow.

She developed a case of pellagra, and this disease gradually sapped her remaining strength, finally resulting in death at her home in Decatur, November 27, 1910.

[2] The Missouria H. Stokes Papers, including correspondence related to personal affairs, temperance, and religion,[10] are held in the Special Collections at the Perkins Library of Duke University.