Except for a short section which overlaps Route 13, it is a two-lane highway its entire length.

Two miles west (at Umber View Heights), the highway crosses Stockton Lake and enters Stockton State Park.

East of Bona, it crosses yet another arm of Stockton Lake, then begins a six-mile (9.7 km) concurrency with Route 123.

Seventeen miles (27 km) east of Eudora, the highway joins Route 13 for one mile (1.6 km), then turns east going through Pleasant Hope, Goodnight, and Tin Town.

The highway continues east to County Road 65 (former 65) follows it then goes east where Route 215 concludes at US 65 at a Michigan left style junction where the highway continues as Route O.