After performing with many different bands around the Detroit area, her first big break came when she was selected as a replacement for Caroline Crawford to be the lead singer for Bohannon.
[2][3] In 2009, along with Motown Alumni Association President Billy Wilson, she helped to create the Detroit Black Music Awards, which are held annually on the first Sunday of August, at the Charles H. Wright Museum of African American History.
[5] To celebrate John Lee Hooker's 100th birthday anniversary in 2017, Misty Love joined drummer Muruga Booker, Rock & Roll Hall of Fame inductee guitarist J.C. "Billy" Davis, P-Funk guitarist Tony "Strat" Thomas, and bassist John Sauter to form the Booker Blues All-Stars, and released the album, Booker Plays Hooker.
[citation needed] Misty also received a platinum CD for singing behind Kid Rock and Sheryl Crow on their 2003 hit song "Picture".
[citation needed] Misty Love performed on "Standing in the Shadows of Motown", which won the 2003 Grammy Award for Best Compilation Soundtrack for Visual Media.