[2] Mithoon launched the singer Arijit Singh in 2011 with Mohammad Irfan Ali co-singer with the song Phir Mohabbat.

His grandfather, Pandit Ram Prasad Sharma, imparted music knowledge to thousands of aspirants, many of whom are amongst today's top musicians.

[3] His father, Naresh Sharma, was a leading expert of musical arrangements,[4] having worked with almost all of the top composers in more than two hundred movies.

In 2006, Mithoon's friend recommended his name to Onir, (director of Bas Ek Pal), who wanted an electro-based title track.

[10] He has also been a solo or guest composer for movies such as Jism 2, Yaariyan, Ek Villain, Hate Story 2, Creature 3D, Samrat & Co, Alone, Hamari Adhuri Kahani, Bhaag Johnny, All Is Well, Loveshhuda, Sanam Re, Ki & Ka, Shivaay, Wajah Tum Ho, Half Girlfriend, Aksar 2, Hate Story 4, Baaghi 2, Kabir Singh, Mercury, Khuda Haafiz, Radhe Shyam and Gadar 2.