[4] Mitragyna parvifolia fresh leaf sap is used by the tribals in treatment of jaundice in the Chenchus, Yerukalas, Yanadis and Sugalis of Gundur District, Andhra Pradesh.

Its stem bark is used in treatment of biliousness and muscular pains by the local inhabitant of Tumkur district, Karnataka, India.

The tribals of Sonaghati of Sonbhadra district, Uttar Pradesh heal fever by a decoction of the M. parvifolia bark.

Valaiyans tribe, population of Sirumalai hills, Madurai district, Western Ghats, Tamil Nadu use stem bark for rheumatic pain.

The bark and roots are used to treat fever, colic, muscular pain, burning sensation, poisoning, gynecological disorders, cough, and edema, and as an aphrodisiac.