[2] After her announcement on July 14, 2015, Matsuki had been under treatment for acute pneumonia until her death on October 27, 2015, in Tokyo from lymphoma caused by chronic active EBV infection.

[3][4][5][6][7] At the time of her death, she was cast as Charlotte Dimandias in the anime Hundred.

[3] Her scheduled and ongoing roles were taken over by Yui Horie,[8][9] Yumi Kakazu,[10][11] Reina Ueda[12] and Noriko Shitaya.

[13][14] A charity event in her honour was held on September 11, 2016, at the Science Museum Hall in Chiyoda Ward, Tokyo, Japan.

Miyu-chan event organized by her friends and colleagues had its proceeds go towards CAEBV research and related medical causes.